Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Open breast biopsy. A critical analysis.

J H Shroff1, L R Lloyd, D M Schroder

  • 1Department of Surgery, St. John Hospital and Medical Center, Detroit, Michigan 48236.

The American Surgeon
|August 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intraoperative and early postoperative gastric intramucosal pH predicts morbidity and mortality after major abdominal surgery.

The American surgeon·2001
Same author

The advanced breast biopsy instrumentation (ABBI) experience at a community hospital.

The American surgeon·1999
Same author

Elective conventional colectomy in the era of laparoscopic surgery.

The American surgeon·1996
Same author

Laparoscopic cholecystectomy for gallbladder torsion.

Surgical laparoscopy & endoscopy·1995
Same author

Laparoscopic appendectomy for acute appendicitis: is there really any benefit?

The American surgeon·1993
Same author

The Küttner dissector as a familiar aid in performing laparoscopic cholecystectomy.

Surgery, gynecology & obstetrics·1991
Same journal

Impact of Ceftriaxone on the Incidence of Early VAP in Patients With TBI and Multisystem Trauma.

The American surgeon·2026
Same journal

Physiologic Status at Cannulation Is Associated With Survival in Trauma Patients Receiving ECMO.

The American surgeon·2026
Same journal

Robotic Resection of Type 2 Klatskin's Tumor With Portal Vein Lateral Venorrhaphy and Dual Hepaticojejunostomy Biliary Reconstruction.

The American surgeon·2026
Same journal

Artificial Intelligence in Everyday Surgical Practice: A Practical Review.

The American surgeon·2026
Same journal

What the Salary Rankings Miss About Pediatric Surgery: Readiness, Not Compensation.

The American surgeon·2026
Same journal

Contrast Without Clarity: The Questionable Role of Oral Contrast in Detecting Missed Hollow Viscus Injury.

The American surgeon·2026
See all related articles

Biopsying nonpalpable breast lesions detected by mammography leads to earlier cancer detection. Older age, mammogram findings, and palpable lesions are key predictors of malignancy.

Area of Science:

  • Radiology
  • Oncology
  • Pathology

Background:

  • Assessing breast cancer malignancy rates is crucial for early detection and improved patient outcomes.
  • Understanding factors influencing malignancy risk aids in diagnostic strategies.

Purpose of the Study:

  • To compare the malignancy rate of open breast biopsies with literature data.
  • To evaluate the impact of biopsying nonpalpable mammographically detected lesions on cancer staging.
  • To identify predictors of malignancy in breast lesions.

Main Methods:

  • Retrospective review of 518 open breast biopsies performed between January 1, 1988, and December 31, 1988.
  • Analysis of patient demographics, lesion characteristics (palpable vs. nonpalpable, mammographic findings), and malignancy rates.

Related Experiment Videos

  • Comparison of cancer staging for palpable and nonpalpable lesions.

    • Main Results:

    • Overall malignancy rate was 23.6% (122/518).
    • Nonpalpable lesions had a 17.5% malignancy rate, with a higher proportion of early-stage cancers (28% tumor in situ, 60% stage 1).
    • Palpable lesions showed a higher malignancy rate (29.0%) and included more advanced stages.
    • Malignancy rates were significantly higher in patients over 40 (28.6% vs. 6.7%) and for lesions visible on mammography (25.3% vs. 14.2%).

    Conclusions:

    • Biopsy of nonpalpable mammographically detected lesions facilitates earlier breast cancer diagnosis.
    • Age over 40, mammographic evidence of a lesion, and palpable lesions are significant predictors of malignancy.
    • No single factor definitively ruled out malignancy, underscoring the importance of biopsy.