Related Experiment Video
Updated: Jun 24, 2026

Precision Implementation of Minimal Erythema Dose (MED) Testing to Assess Individual Variation in Human Inflammatory Response
Published on: October 3, 2019
Methods for assessment of cutaneous ageing
1Department of Medicine (Dermatology), University of Wales College of Medicine, Heath Park, Cardiff CF4 4XN, UK.
Accurately measuring skin aging requires distinct methods for intrinsic and environmentally-induced aging. No single technique can fully assess cutaneous aging, necessitating a combination of approaches for comprehensive evaluation.
Area of Science:
- Dermatology and Gerontology
- Cosmetic Science
Background:
- Quantitative assessment of skin aging is crucial for evaluating anti-aging treatments.
- Distinguishing between intrinsic aging and environmentally-induced aging (photoaging) is essential.
- Current methods for assessing skin aging vary in invasiveness and specificity.
Purpose of the Study:
- To review methods for quantitative skin aging assessment.
- To highlight the need for tailored techniques based on treatment goals.
- To emphasize the importance of differentiating intrinsic and extrinsic aging factors.
Main Methods:
- Discussion of both invasive and non-invasive techniques for skin aging evaluation.
- Examples include topical retinoic acid's effects on epidermal thickness (invasive) and stratum corneum replacement time (non-invasive).
- Mention of profilometry, ultrasound for skin thickness, and skin color measurement as relevant techniques.
Main Results:
- Various aspects of skin structure and function change with age.
- Specific techniques can quantify changes related to intrinsic aging and photoaging.
- Combined methods provide a more comprehensive assessment of skin aging.
Conclusions:
- No single method is sufficient for a complete assessment of cutaneous aging.
- A combination of invasive and non-invasive techniques is often necessary.
- Assessment should differentiate between intrinsic aging and environmentally-induced damage, particularly solar elastotic changes.
Related Concept Videos
Changes in Skin Color: Clinical Perspectives
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
The Effect of Aging on Tissues
Assessment of the Cardiovascular System II: Inspection
Head and Neck
Assessment of Airway, Skin Color, and Use of Accessory Muscles
Introduction
The initial evaluation of a patient's respiratory system...