Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Association Areas of the Cortex01:21

Association Areas of the Cortex

Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex.
Anatomy of the Eyeball01:20

Anatomy of the Eyeball

The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle layer, the vascular tunic,...
Vision01:24

Vision

Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
Visual System01:26

Visual System

Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
Once through the pupil, the light passes through the lens, a...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Regular light-intensity exercise accelerates contextual fear extinction with reduced dorsal CA3 activation in male rats.

Neurochemistry international·2026
Same author

Microfluidic platforms for probing spontaneous functional recovery in hierarchically modular neuronal networks.

Communications engineering·2026
Same author

Internal neurolysis for trigeminal neuralgia without apparent vascular compression: Clinical outcomes and intraoperative electrophysiological conduction changes.

Surgical neurology international·2026
Same author

Enigmatic Role of IL-31 in the Itch and Inflammation of Vernal Keratoconjunctivitis.

Juntendo medical journal·2026
Same author

Increased Elbow Valgus Torque During Pitching Is Not a Risk Factor for Medial Elbow Injuries in Young Baseball Pitchers: A Prospective Cohort Study.

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association·2026
Same author

Internal neurolysis for atypical facial pain: Clinical outcomes and validation of an intraoperative trigeminal pathology scoring system.

Surgical neurology international·2026

Related Experiment Video

Updated: Jun 24, 2026

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex
08:42

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex

Published on: February 8, 2020

Surround suppression sharpens orientation tuning in the cat primary visual cortex.

Masahiro Okamoto1, Tomoyuki Naito, Osamu Sadakane

  • 1Graduate School of Frontier Biosciences, Osaka University, Toyonaka, Osaka, Japan.

The European Journal of Neuroscience
|March 18, 2009
PubMed
Summary

Surround suppression in the primary visual cortex (V1) sharpens orientation tuning. This visual processing mechanism enhances orientation discrimination for large objects with uniform patterns.

More Related Videos

Investigating the Deployment of Visual Attention Before Accurate and Averaging Saccades via Eye Tracking and Assessment of Visual Sensitivity
06:46

Investigating the Deployment of Visual Attention Before Accurate and Averaging Saccades via Eye Tracking and Assessment of Visual Sensitivity

Published on: March 18, 2019

Non-aversive Animal Restraint Enabling Recording of Optomotor Reflex in Ground Squirrels
07:28

Non-aversive Animal Restraint Enabling Recording of Optomotor Reflex in Ground Squirrels

Published on: July 25, 2025

Related Experiment Videos

Last Updated: Jun 24, 2026

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex
08:42

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex

Published on: February 8, 2020

Investigating the Deployment of Visual Attention Before Accurate and Averaging Saccades via Eye Tracking and Assessment of Visual Sensitivity
06:46

Investigating the Deployment of Visual Attention Before Accurate and Averaging Saccades via Eye Tracking and Assessment of Visual Sensitivity

Published on: March 18, 2019

Non-aversive Animal Restraint Enabling Recording of Optomotor Reflex in Ground Squirrels
07:28

Non-aversive Animal Restraint Enabling Recording of Optomotor Reflex in Ground Squirrels

Published on: July 25, 2025

Area of Science:

  • Neuroscience
  • Visual Neuroscience

Background:

  • Neurons in the primary visual cortex (V1) exhibit surround suppression, where responses are inhibited by stimuli outside the classical receptive field (CRF).
  • Orientation tuning sharpness in V1 neurons increases with stimulus size beyond the CRF.

Purpose of the Study:

  • To quantitatively investigate the relationship between orientation tuning sharpening and surround suppression in V1.
  • To determine the functional role of surround suppression in visual perception.

Main Methods:

  • Recorded responses from 73 V1 neurons in anesthetized cats.
  • Utilized sinusoidal grating patches to stimulate classical receptive field (CRF) and extraclassical receptive field (ECRF).

Main Results:

  • A significant correlation was found between the strength of surround suppression and the sharpening of orientation tuning for stimuli covering both CRF and ECRF.
  • Simulation analysis indicated that broadly tuned surround suppression sharpens orientation tuning for large gratings without altering the optimal orientation.

Conclusions:

  • Surround suppression in V1 plays a functional role in enhancing orientation discrimination for large, uniformly patterned objects.
  • This mechanism contributes to improved visual perception of complex stimuli.