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The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications
Published on: October 7, 2016
Synthesis and characterization of a hydrogel with therapeutic applications
Loredana Elena Niţă1, Iordana Neamţu, Aurica P Chiriac
1"Petru Poni" Institute of Macromolecular Chemistry Iaşi, Department of Polymeric Materials.
Abstract:
The study presents the synthesis of an acrylamide polymeric hydrogel in aqueous solution by copolymerization concomitant with a crosslinking process using a bifunctional co-monomer with a redox initiation system--potassium peroxo-disulphate/ascorbic acid. The swelling kinetics as well the characterization of structure through optical microscopy was performed. The synthesized polymeric gel shows temperature sensitivity, maintaining low temperatures for a prolonged period of time. Thus, the material is assessed as an inner material in thermo sensitive packs to be applied in pain therapy.

