A rare case of signet ring cell gastric adenocarcinoma

Although the incidence and mortality rates continue to decline in the United States, gastric cancer remains one of the leading causes of cancer mortality worldwide. Signet Ring Cell gastric cancer is a rare and distinct histological subtype. This is a case report of an individual who presented with nausea, vomiting, abdominal pain and weight loss. The patient was found to have a large, obstructing antral mass that was biopsied by esophagogastroduodenoscopy (EGD) and revealed Signet Ring Cell gastric adenocarcinoma. Preoperative staging with positron emission tomography (PET) and computed tomography (CT) scan displayed multiple pulmonary nodules felt to be consistent with sarcoidosis after transbronchial biopsy results were obtained. Patient was taken to surgery for curative resection and lymph node dissection, but peritoneal metastatic disease was found intra-operatively. Gastric carcinoma frequently requires a multi-disciplinary approach to properly diagnose, stage, and treat.