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Related Experiment Video

Updated: Jun 24, 2026

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability

Published on: July 25, 2025

Lumbar disk replacement with the ProDisc prosthesis.

Yigal Mirovsky¹, Ehud Shalmon, Zvi Halpern

¹Spine Unit, Assaf Harofeh Medical Center, Zerifin 73000, Israel.

|March 19, 2009

Summary

This summary is machine-generated.

The ProDisc II prosthesis effectively reduced pain and disability in patients with degenerative disk disease. However, prior surgery at the same level or adjacent to fusion impacted outcomes.

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Full-Endoscopic Transforaminal Approach for Lumbar Discectomy

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Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability

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Full-Endoscopic Transforaminal Approach for Lumbar Discectomy

Full-Endoscopic Transforaminal Approach for Lumbar Discectomy

Published on: September 8, 2023

Area of Science:

Orthopedic Surgery
Spinal Arthroplasty
Degenerative Disc Disease

Background:

Degenerative disc disease (DDD) significantly impacts patient quality of life.
Spinal arthroplasty offers a motion-preserving alternative to fusion for DDD.

Purpose of the Study:

To evaluate the clinical and radiographic outcomes of the ProDisc II total disc replacement for lumbar DDD.
To identify factors influencing the success of lumbar total disc replacement.

Main Methods:

Twenty-two ProDisc II prostheses were implanted in 21 patients with lumbar DDD at L5-S1 or L4-L5.
Clinical outcomes were assessed using Visual Analog Scale (VAS) for pain and Oswestry Disability Index (ODI).
Radiographic evaluation assessed disk space height reconstruction.

Main Results:

Significant improvements in VAS pain scores (7.7 to 4.6) and ODI (61 to 35) were observed (P<.001).
Successful reconstruction of disk space height was achieved in all patients.
Previous diskectomy and adjacent segment degeneration negatively affected outcomes.

Conclusions:

ProDisc II total disc replacement is an effective treatment for lumbar degenerative disc disease, improving pain and function.
Patient history, including prior surgical interventions and adjacent segment health, should be considered when evaluating potential candidates for disc replacement.