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Updated: Jun 24, 2026

Uniportal Full Endoscopic Posterolateral Transforaminal Lumbar Interbody Fusion
Published on: June 6, 2025
Conservative follow-up after epidural abscess and diskitis complicating instrumented metal interbody cage
Yasuaki Tokuhashi1, Yasumitsu Ajiro, Natsuki Umezawa
1Department of Orthopedic Surgery, Nihon University School of Medicine, 30-1 Oyaguchi-kamimachi, Itabashi-ku, Tokyo, Japan.
Abstract:
There have been few reports on the imaging diagnosis and treatment of infection of interbody cages used in posterior lumbar interbody fusion. Even in a patient undergoing posterior lumbar interbody fusion using a metal cage, magnetic resonance imaging (MRI) might be able to diagnose epidural abscesses and diskitis when titanium alloy implants are used. When infection of the instrumented cage is diagnosed, emergency debridement with or without removal of implants, including the cage, appropriate wound closure, and the administration of potent antibiotics is the standard treatment. This article describes the conservative follow-up of a patient with epidural abscess and diskitis following instrumented posterior lumbar interbody fusion using a metal cage without surgical intervention. A 40-year-old man had undergone instrumented posterior lumbar interbody fusion at the L5/S1 level approximately 1 year previously. He suddenly developed a fever (temperature, 38 degrees C) and severe lower back pain without apparent cause. Late infection was suspected from his symptoms and laboratory findings, and a wide spectrum antibiotic was administered. On MRI, the low and high signal areas near the end-plate of L5/S1 were detected by T1- and T2-weighted imaging, respectively, and an abscess was noted around the cage. We recommended debridement as treatment; however, he refused further surgical intervention by reason of symptomatic remission. Therefore, wide spectrum antibiotics were continued. Fortunately, no lower back pain has recurred. Examination by MRI during the clinical course clarified the presence and disappearance of an epidural abscess and diskitis. Although the outcome of this case was fortunate, this conservative treatment is unusual, and is not recommended as standard treatment.
Insights
This case study highlights a rare instance of successfully treating late-onset infection after posterior lumbar interbody fusion using conservative antibiotic therapy, avoiding surgery for an epidural abscess and diskitis.
Area of Science:
- Spinal Surgery
- Infectious Diseases
- Radiology
Background:
- Posterior lumbar interbody fusion (PLIF) with metal cages can lead to late-onset infections, including epidural abscesses and diskitis.
- Imaging, particularly magnetic resonance imaging (MRI), plays a crucial role in diagnosing these infections, even with titanium alloy implants.
- Standard treatment for infected interbody cages involves prompt surgical debridement and antibiotic administration.
Observation:
- A 40-year-old male presented with fever and severe back pain one year post-PLIF.
- MRI revealed an epidural abscess and diskitis around the L5/S1 interbody cage.
- The patient refused surgical intervention due to symptomatic improvement after initiating broad-spectrum antibiotics.
Findings:
- Conservative management with continued broad-spectrum antibiotics led to the resolution of the epidural abscess and diskitis.
- Serial MRI examinations confirmed the disappearance of the infection.
- The patient experienced no recurrence of lower back pain.
Implications:
- This case demonstrates a potential, albeit unusual, conservative treatment pathway for late-onset cage infections following PLIF.
- While successful in this instance, conservative management is not recommended as standard practice.
- Further research is needed to explore non-surgical options for spinal implant infections.
