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Updated: Jun 24, 2026

Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models
Published on: October 28, 2021
Low-grade intramedullary osteosarcoma of the tibia presenting as an intracortical lesion
Janet Sailor1, Edward F McCarthy, Kristy L Weber
1Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins School of Medicine, 600 N Wolfe St, Baltimore, MD 21287, USA.
Abstract:
Intramedullary or intraosseous osteosarcomas are the most common subtype of osteosarcoma, followed in frequency by parosteal and periosteal osteosarcomas, with intracortical osteosarcomas representing the rarest type. The diagnosis and classification of osteosarcomas can be complicated or delayed when these lesions masquerade as benign bone lesions. This article presents a case of a low-grade osteosarcoma arising in the tibia of a 19-year-old man, which had radiographic features most suggestive of a benign entity.

