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Stabilization of RNA oligomers through reverse micelle encapsulation

Hillary Workman1, Peter F Flynn

  • 1Department of Chemistry, 315 South 1400 East Room 2020, University of Utah, Salt Lake City, Utah 84112, USA.

Journal of the American Chemical Society
|March 19, 2009
PubMed
Summary

Cellular crowding enhances the stability of RNA oligonucleotides, such as TAR RNA and U4 snRNA. This finding suggests RNA molecules gain significant stability under physiological conditions.

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