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Related Concept Videos

Neurulation01:30

Neurulation

Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the anterior...
Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
Cranial and Spinal Meninges01:19

Cranial and Spinal Meninges

The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
Increased Intracranial Pressure ll: Pathophysiology01:29

Increased Intracranial Pressure ll: Pathophysiology

Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...
Cranial Bones: Superior and Posterior View01:14

Cranial Bones: Superior and Posterior View

The superior view of the cranium shows the frontal and paired parietal bones.
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
Vertebral Column: Regions and Curvature01:16

Vertebral Column: Regions and Curvature

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Updated: Jun 24, 2026

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model
05:12

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model

Published on: September 4, 2017

Chiari malformations.

Donna L Caldwell1, Cheryl O Dubose, Tracy B White

  • 1Arkansas State University, Jonesboro, Arkansas, USA.

Radiologic Technology
|March 19, 2009
PubMed
Summary
This summary is machine-generated.

Chiari malformations present diagnostic challenges due to varied symptoms that mimic other neurological conditions. Magnetic resonance imaging is crucial for accurate diagnosis and treatment planning.

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Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model
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Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
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Area of Science:

  • Neurology
  • Radiology
  • Medical Diagnostics

Background:

  • Chiari malformations are serious neurological conditions.
  • Diagnosis can be challenging for clinicians.
  • Symptoms often overlap with other neurological disorders.

Purpose of the Study:

  • To highlight the diagnostic complexities of Chiari malformations.
  • To emphasize the role of imaging in managing these conditions.

Main Methods:

  • Review of clinical presentations of Chiari malformations.
  • Emphasis on the utility of magnetic resonance imaging (MRI).

Main Results:

  • Chiari malformations can be asymptomatic or present with diverse symptoms.
  • Symptoms may be misdiagnosed as other neurological conditions.
  • MRI is a key tool for diagnosis.

Conclusions:

  • Accurate diagnosis of Chiari malformations requires careful evaluation.
  • Magnetic resonance imaging is essential for effective diagnosis and treatment strategies.