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The human body harbors a vast and diverse viral community known as the human virome. The virome includes bacteriophages that infect bacteria, and eukaryotic viruses that infect human cells. Transient dietary and environmental viruses also contribute to this dynamic ecosystem. Estimates suggest the human body may contain on the order of 10¹³ viral particles, though abundance varies widely by body site and detection method.Comprehensive characterization of the virome has become possible only with...
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CHPVDB--a sequence annotation database for Chandipura virus.

Manas Ranjan Dikhit1, Sindhu Prava Rana, Pradeep Das

  • 1BioMedical Informatics Division, Rajendra Memorial Research Institute of Medical Sciences, Agam Kuan, Patna, India - 800007.

Bioinformation
|March 19, 2009
PubMed
Summary

A new database, CHPVDB, integrates Chandipura virus (CHPV) proteomic data. This resource aids virologists by linking molecular analysis, cleavage sites, and protein functions, enhancing viral research.

Keywords:
CHPVCHPVDBChandipura virusdatabaseproteinssequences

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Area of Science:

  • Virology
  • Bioinformatics
  • Proteomics

Background:

  • Proteomic databases are crucial for virology.
  • A growing need exists for integrated data resources.
  • The gap between sequence data and functional characterization is widening.

Purpose of the Study:

  • To create a centralized database for Chandipura virus (CHPV) proteomic information.
  • To provide virologists with a one-step information center.
  • To integrate diverse research data into a single resource.

Main Methods:

  • Developed CHPVDB, a novel database.
  • Integrated protein information from existing databases, servers, and reports.
  • Utilized SVMProt and related tools for protein functional family assignment.

Main Results:

  • CHPVDB provides a unified resource for CHPV protein data.
  • Facilitated analysis of relationships between molecular characteristics and protein functions.
  • Enabled assignment of protein functional families using computational tools.

Conclusions:

  • CHPVDB serves as a valuable, integrated information center for virologists.
  • The database enhances the understanding of CHPV proteins.
  • Facilitates molecular analysis and functional characterization of viral proteins.