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Updated: Jun 24, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
A review of aggressive periodontitis and an associated case report
Seamus Sharkey1, Aifric Nic Chaollai, Michael O'Sullivan
1Department of Restorative Dentistry and Periodontology Dublin Dental School, Dublin, Ireland.
Abstract:
Aggressive periodontitis is a debilitating oral disease that results in rapid destruction of the periodontal tissues. It has recently been reclassified and ongoing efforts are now being made to understand its pathogenesis and record its prevalence in the population. This case report gives a brief outline of studies that have investigated why this disease tends to occur in otherwise young healthy adults. The mechanisms behind such extensive periodontal damage are discussed. A case report of a patient with aggressive periodontitis, treated in the Dublin Dental School and Hospital, is presented and the rationale behind his treatment is discussed.
