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Related Experiment Videos

Encephalomyelitis with seroconversion to Listeria monocytogenes.

P Baxter1, D Gardner-Medwin, D Bates

  • 1Department of Paediatric Neurology, Newcastle General Hospital.

Archives of Disease in Childhood
|September 1, 1991
PubMed
Summary

A previously healthy girl recovered from brain stem encephalomyelitis. Despite negative cultures, Listeria monocytogenes serotype 4 infection was confirmed, suggesting antilisterial treatment for similar cases.

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Area of Science:

  • Neurology
  • Infectious Diseases
  • Microbiology

Background:

  • Lymphocytic encephalomyelitis is a rare neurological condition affecting the brain stem.
  • Diagnosis can be challenging, especially with negative initial cultures.

Observation:

  • A previously healthy pediatric patient presented with symptoms of encephalomyelitis.
  • The patient received standard antibiotic and steroid therapy.
  • Cerebrospinal fluid and blood cultures were negative for pathogens.

Findings:

  • The patient seroconverted to Listeria monocytogenes serotype 4, indicating a past infection.
  • Recovery was observed following the initial treatment regimen.

Implications:

Related Experiment Videos

  • Listeria monocytogenes should be considered in the differential diagnosis of unexplained encephalomyelitis, even with negative cultures.
  • Serological testing for Listeria monocytogenes is crucial in similar clinical presentations.
  • Antilisterial treatment may be beneficial in specific cases of encephalomyelitis with suspected Listeria infection.