Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

Positron Emission Tomography

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Retraction: Nitric Oxide Induces Hypoxia-inducible Factor 1 Activation That Is Dependent on MAPK and Phosphatidylinositol 3-Kinase Signaling.

The Journal of biological chemistry·2025

Same author

Retraction: Induction of Hypoxia-inducible Factor 1 Activity by Muscarinic Acetylcholine Receptor Signaling.

The Journal of biological chemistry·2025

Same author

Long-term results of dynamic tumor-tracking stereotactic body radiotherapy with real-time monitoring using a gimbal-mounted linac for liver tumors: a multicenter observational study.

International journal of clinical oncology·2025

Same author

Multi-Institutional Phase II Study on the Efficacy and Safety of Dynamic Tumor-Tracking, Moderately Hypofractionated Intensity-Modulated Radiotherapy in Patients With Locally Advanced Pancreatic Cancer.

Cancer medicine·2025

Same author

Prospective external validation of radiomics-based predictive model of distant metastasis after dynamic tumor tracking stereotactic body radiation therapy in patients with non-small-cell lung cancer: A multi-institutional analysis.

Journal of applied clinical medical physics·2024

Same author

Epitope binning for multiple antibodies simultaneously using mammalian cell display and DNA sequencing.

Communications biology·2024

Search research articles

Related Experiment Video

Updated: Jun 24, 2026

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

[Molecular imaging--diagnosis by functional imaging].

Shinae Kizaka-Kondoh¹, Masahiro Hiraoka

¹Dept. of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine.

Gan to Kagaku Ryoho. Cancer & Chemotherapy

|March 20, 2009

Summary

Diagnostic imaging is evolving from structural visualization to molecular-level functional analysis. Innovations in optical imaging promise to revolutionize whole-body diagnostics by integrating structural and functional data.

More Related Videos

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT

Functional Imaging of Brown Fat in Mice with ¹⁸F-FDG micro-PET/CT

Published on: November 23, 2012

MRI and PET in Mouse Models of Myocardial Infarction

MRI and PET in Mouse Models of Myocardial Infarction

Published on: December 19, 2013

Related Experiment Videos

Last Updated: Jun 24, 2026

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT

Functional Imaging of Brown Fat in Mice with ¹⁸F-FDG micro-PET/CT

Published on: November 23, 2012

MRI and PET in Mouse Models of Myocardial Infarction

MRI and PET in Mouse Models of Myocardial Infarction

Published on: December 19, 2013

Area of Science:

Medical imaging technologies
Biomedical instrumentation
Optical physics

Context:

20th-century advancements enabled noninvasive structural imaging (e.g., MRI, CT).
21st-century focus shifts to molecular-level, whole-body analysis (post-genomic era).
Integration of structural and functional information is the next frontier.

Purpose:

To highlight the transition from structural to functional diagnostic imaging.
To discuss the role of technological innovation, particularly optical imaging, in this evolution.
To explore the potential of multimodality in diagnostic instruments.

Summary:

Technological progress has driven diagnostic imaging from observing tissue structure to analyzing molecular-level functions.
Optical imaging is key to developing multimodality instruments, merging techniques like MRI and CT with molecular probes.
Future noninvasive imaging will incorporate functional data, advancing beyond current structural insights.

Impact:

Optical imaging's versatility may revolutionize diagnostic capabilities.
Multimodal imaging will provide comprehensive, integrated health assessments.
This shift promises more precise and personalized medical diagnostics.