Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 24, 2026

Ex Situ Normothermic Machine Perfusion of Donor Livers
12:13

Ex Situ Normothermic Machine Perfusion of Donor Livers

Published on: May 26, 2015

Normothermic perfusion: a mini-review.

Srikanth P Reddy1, Jens Brockmann, Peter J Friend

  • 1Nuffield Department of Surgery, University of Oxford, Oxford, United Kingdom.

Transplantation
|March 20, 2009
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Urine Recirculation During Normothermic Kidney Preservation Improves Energy Balance Involving the Urea and Citric Acid Cycles.

Transplantation direct·2026
Same author

Evaluation of the Prevalence of Occult Fibrin in Donor Organs, Its Origins, and Consequences: Insights From the COPE Studies.

Transplant international : official journal of the European Society for Organ Transplantation·2026
Same author

The IDEAL framework for machine perfusion in liver transplantation.

Nature reviews. Gastroenterology & hepatology·2025
Same author

Consensus classification of biliary complications after liver transplantation: guidelines from the BileducTx meeting.

The British journal of surgery·2025
Same author

Regulatory T cell therapy is associated with distinct immune regulatory lymphocytic infiltrates in kidney transplants.

Med (New York, N.Y.)·2024
Same author

Defatting of donor transplant livers during normothermic perfusion-a randomised clinical trial: study protocol for the DeFat study.

Trials·2024
Same journal

Filtered or Fried? Rethinking Intraoperative Cell Salvage in Liver Transplantation.

Transplantation·2026
Same journal

Simultaneous Liver-kidney Versus Liver Transplantation Categorized by Pretransplant eGFR: Impact of the 2017 OPTN Policy.

Transplantation·2026
Same journal

Preformed Anti-DQ Alpha Donor-specific Antibodies and the Risk of Antibody-mediated Rejection After Kidney Transplantation.

Transplantation·2026
Same journal

People in Transplantation: Professor Nadey Hakim, MD, PhD, FRCS, FRCSGlas (Hon), FACS, President-Elect of The Transplantation Society.

Transplantation·2026
Same journal

IL-1 Receptor Blockade Modulates Inflammation During Sequential Perfusion in Ex Vivo Porcine Kidneys.

Transplantation·2026
Same journal

Regulatory T Cells Allosensitized Under the Blockade of CD80/CD86-CD28 Costimulation Prolonged Islet Allograft Survival.

Transplantation·2026
See all related articles

Normothermic preservation improves organ transplant outcomes by extending preservation times and allowing viability assessment. This technique is key to utilizing more marginal donor organs for transplantation.

Area of Science:

  • Transplantation science
  • Organ preservation technologies

Background:

  • Organ preservation quality is crucial for transplantation success.
  • Current preservation methods limit the use of marginal donor organs.

Purpose of the Study:

  • To highlight the benefits of normothermic preservation.
  • To emphasize its role in overcoming limitations in organ transplantation.

Main Methods:

  • Normothermic preservation (NP) at physiological temperature.
  • Assessment of prolonged preservation capabilities.
  • Evaluation of resuscitation after warm ischemia.
  • Organ viability assessment pre-transplantation.

Main Results:

  • Normothermic preservation enables extended organ preservation.

More Related Videos

An Open-Source Normothermic Perfusion System Designed for Research Scientists
11:23

An Open-Source Normothermic Perfusion System Designed for Research Scientists

Published on: July 18, 2025

Normothermic Ex Vivo Liver Machine Perfusion in Mouse
13:14

Normothermic Ex Vivo Liver Machine Perfusion in Mouse

Published on: September 25, 2023

Related Experiment Videos

Last Updated: Jun 24, 2026

Ex Situ Normothermic Machine Perfusion of Donor Livers
12:13

Ex Situ Normothermic Machine Perfusion of Donor Livers

Published on: May 26, 2015

An Open-Source Normothermic Perfusion System Designed for Research Scientists
11:23

An Open-Source Normothermic Perfusion System Designed for Research Scientists

Published on: July 18, 2025

Normothermic Ex Vivo Liver Machine Perfusion in Mouse
13:14

Normothermic Ex Vivo Liver Machine Perfusion in Mouse

Published on: September 25, 2023

  • The technique facilitates resuscitation following warm ischemic injury.
  • Viability can be assessed before transplantation using NP.

    • Conclusions:

    • Normothermic preservation is a vital technology for improving organ transplantation.
    • It expands the potential use of marginal donor organs.
    • NP offers enhanced organ quality and assessment before implantation.