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Updated: Jun 24, 2026

Murine Intrapulmonary Tracheal Transplantation: A Model for Investigating Obliterative Airway Disease After Lung Transplantation
Published on: November 10, 2023
Lung cavitation due to Mycobacterium xenopi in a renal transplant recipient
L Martín-Penagos1, E Rodrigo, J C Ruíz
1Department of Nephrology, University Hospital Marqués de Valdecilla Santander, Santander (Cantabria), Spain. luismartinpenagos@hotmail.com
Abstract:
Mycobacterium xenopi is an unusual pathogen and few such cases have been reported in the literature. We report the case of a patient with a sirolimus-based immunosuppressive regimen, who developed lung cavitation. M. xenopi was isolated from the sputum. The patient was treated initially with rifampicin, isoniazid, and pyrazinamide; levofloxacin was added to the treatment regimen after M. xenopi was demonstrated. A possible relationship between sirolimus and M. xenopi infection has been postulated, probably due to the combination of pulmonary toxicity and cellular immunosuppression of rapamycin.
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