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Updated: Jun 24, 2026
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Development and Functional Characterization of Murine Tolerogenic Dendritic Cells
Published on: May 18, 2018
2-Azidoalkoxy-7-hydro-8-oxoadenine derivatives as TLR7 agonists inducing dendritic cell maturation
Jimmy J Weterings1, Selina Khan, Gerbrand J van der Heden van Noort
1Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
Bioorganic & Medicinal Chemistry Letters
|March 21, 2009
Abstract:
The synthesis of an array of 2-azidoalkoxy substituted 7-hydro-8-oxoadenines is described. The relation of the structure of these compounds and their ability to induce maturation of dendritic cells is evaluated.
