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Updated: Jun 24, 2026
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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Theoretic basis and technical implementations of CT perfusion in acute ischemic stroke, part 2: technical
A A Konstas1, G V Goldmakher, T-Y Lee
1Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA. akonstas@partners.org
AJNR. American Journal of Neuroradiology
|March 21, 2009
Summary
CT perfusion (CTP) is a functional brain imaging technique. It helps assess blood flow and volume, crucial for diagnosing stroke and other neurovascular conditions by identifying salvageable brain tissue.
Area of Science:
- Neurology
- Radiology
- Medical Imaging
Background:
- CT perfusion (CTP) offers insights into capillary-level brain hemodynamics.
- It complements unenhanced CT and CT angiography for neurovascular assessments.
Purpose of the Study:
- To highlight the role of CTP in evaluating acute stroke and vasospasm.
- To explain CTP's critical function in differentiating infarct core from penumbra.
Main Methods:
- Utilizes functional imaging to analyze brain parenchyma hemodynamics.
- Generates parametric maps of cerebral blood flow, cerebral blood volume, and mean transit time.
Main Results:
- CTP provides essential hemodynamic data.
- Enables precise determination of irreversibly infarcted tissue (infarct core).
- Identifies potentially salvageable ischemic tissue (penumbra).
Conclusions:
- CTP is a vital tool in neurovascular imaging.
- It significantly aids in the management of acute stroke and related disorders.
