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Related Concept Videos

Mitosis and Cytokinesis01:35

Mitosis and Cytokinesis

In eukaryotes, the cell division cycle is divided into distinct, coordinated cellular processes that include cell growth, DNA replication/chromosome duplication, chromosome distribution to daughter cells, and finally, cell division. The cell cycle is tightly regulated by its regulatory systems as well as extracellular signals that affect cell proliferation.
The processes of the cell cycle occur over approximately 24 hours (in typical human cells) and in two major distinguishable stages. The...
Mitosis and Cytokinesis02:03

Mitosis and Cytokinesis

In eukaryotes, the cell division cycle is divided into distinct, coordinated cellular processes that include cell growth, DNA replication/chromosome duplication, chromosome distribution to daughter cells, and finally, cell division. The cell cycle is tightly regulated by its regulatory systems as well as extracellular signals that affect cell proliferation.
The processes of the cell cycle occur over approximately 24 hours (in typical human cells) and in two major distinguishable stages. The...
Mitosis And Cytokinesis01:35

Mitosis And Cytokinesis

In eukaryotes, the cell division cycle is divided into distinct, coordinated cellular processes that include cell growth, DNA replication/chromosome duplication, chromosome distribution to daughter cells, and finally, cell division. The cell cycle is tightly regulated by its regulatory systems as well as extracellular signals that affect cell proliferation.
The processes of the cell cycle occur over approximately 24 hours (in typical human cells) and in two major distinguishable stages. The...
Mitosis and Cytokinesis02:03

Mitosis and Cytokinesis

In eukaryotes, the cell division cycle is divided into distinct, coordinated cellular processes that include cell growth, DNA replication/chromosome duplication, chromosome distribution to daughter cells, and finally, cell division. The cell cycle is tightly regulated by its regulatory systems as well as extracellular signals that affect cell proliferation.
The processes of the cell cycle occur over approximately 24 hours (in typical human cells) and in two major distinguishable stages. The...
Determining the Plane of Cell Division02:13

Determining the Plane of Cell Division

Positioning the cell division plane is a critical step during development and cell differentiation, particularly during mitosis when the plane is essential for determining the size of the two daughter cells. The cell division plane is perpendicular to the plane of chromosome segregation, but different types of organisms have different cell division mechanisms to suit their morphology and function. 
Animal cells
In animal cells, the cleavage furrow forms along the plane of cell division starting...
Determining the Plane of Cell Division02:13

Determining the Plane of Cell Division

Positioning the cell division plane is a critical step during development and cell differentiation, particularly during mitosis when the plane is essential for determining the size of the two daughter cells. The cell division plane is perpendicular to the plane of chromosome segregation, but different types of organisms have different cell division mechanisms to suit their morphology and function. 
Animal cells
In animal cells, the cleavage furrow forms along the plane of cell division starting...

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Related Experiment Video

Updated: Jun 24, 2026

Spatiotemporal Analysis of Cytokinetic Events in Fission Yeast
11:19

Spatiotemporal Analysis of Cytokinetic Events in Fission Yeast

Published on: February 20, 2017

Positioning cytokinesis.

Snezhana Oliferenko1, Ting Gang Chew, Mohan K Balasubramanian

  • 1Temasek Life Sciences Laboratory and the Department of Biological Sciences, National University of Singapore, Singapore, Singapore. snejana@tll.org.sg

Genes & Development
|March 21, 2009
PubMed
Summary

Cell division, or cytokinesis, can produce unequal daughter cells by shifting the division machinery. This review explores positioning mechanisms in prokaryotes and eukaryotes, including less-understood cases.

Area of Science:

  • Cell Biology
  • Developmental Biology

Background:

  • Cytokinesis is the final stage of the cell cycle, dividing a mother cell into two daughter cells.
  • Typically, cytokinesis results in daughter cells of similar size, but variations occur in specialized cells or under specific conditions.
  • Asymmetric cell division produces daughter cells of different sizes and often different fates.

Purpose of the Study:

  • To review mechanisms controlling the positioning of the cell division machinery during cytokinesis.
  • To explore how this positioning leads to daughter cells of unequal size and fate.
  • To discuss positioning mechanisms in both prokaryotic and eukaryotic organisms.

Main Methods:

  • Literature review of studies on cell division and cytokinesis.
  • Analysis of mechanisms for positioning the division machinery in various cell types.

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Examination of Mitotic and Meiotic Fission Yeast Nuclear Dynamics by Fluorescence Live-cell Microscopy

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Last Updated: Jun 24, 2026

Spatiotemporal Analysis of Cytokinetic Events in Fission Yeast
11:19

Spatiotemporal Analysis of Cytokinetic Events in Fission Yeast

Published on: February 20, 2017

Reconstitution of Basic Mitotic Spindles in Spherical Emulsion Droplets
10:52

Reconstitution of Basic Mitotic Spindles in Spherical Emulsion Droplets

Published on: August 13, 2016

Examination of Mitotic and Meiotic Fission Yeast Nuclear Dynamics by Fluorescence Live-cell Microscopy
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  • Inclusion of examples from model organisms and non-model systems.

    • Main Results:

    • Cytokinesis positioning is crucial for generating daughter cells with distinct sizes and fates.
    • Mechanisms vary across prokaryotes and eukaryotes, involving complex regulatory pathways.
    • Some cytokinesis-positioning mechanisms remain poorly understood, particularly in non-model systems.

    Conclusions:

    • The precise positioning of the cytokinesis machinery is a fundamental process with significant biological implications.
    • Understanding these mechanisms is key to comprehending cell fate determination and development.
    • Further research is needed to elucidate less-understood cytokinesis-positioning strategies in diverse organisms.