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Biological Samples Preparation for Speciation at Cryogenic Temperature using High-Resolution X-Ray Absorption Spectroscopy
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Published on: May 27, 2022

Serum selenium level in healthy Koreans.

Young-Jae Kim1, Oyunbileg Galindev, Jun Han Sei

  • 1Department of Obstetrics and Gynecology, College of Medicine, Hanyang University, Seoul, South Korea.

Biological Trace Element Research
|March 21, 2009
PubMed
Summary

This study measured serum selenium (Se) levels in healthy Koreans. Females had significantly higher Se levels than males, with no age-related differences observed.

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Published on: August 12, 2018

Area of Science:

  • Biochemistry
  • Trace Element Analysis
  • Human Physiology

Background:

  • Selenium (Se) is an essential trace element vital for antioxidant functions through selenoproteins.
  • Oxidative stress, induced by reactive oxygen species, can be mitigated by adequate selenium levels.
  • Understanding selenium status in human populations is crucial for public health and nutritional guidance.

Purpose of the Study:

  • To determine the mean serum selenium concentrations in healthy Korean adults.
  • To investigate potential differences in serum selenium levels based on gender and age.
  • To establish reference ranges for serum selenium in the Korean population.

Main Methods:

  • Serum samples were collected from 100 healthy Korean volunteers (50 males, 50 females).
  • Inductively coupled plasma-mass spectrometry (ICP-MS) was employed for precise selenium quantification.
  • Data analysis included statistical comparisons for gender and age-related variations.

Main Results:

  • The overall mean serum selenium level was 112.05 ± 30.42 microg/l.
  • Females exhibited significantly higher mean serum selenium levels (120.81 ± 27.37 microg/l) compared to males (103.29 ± 31.05 microg/l) (p = 0.0035).
  • Serum selenium levels showed no statistically significant correlation with age in the studied healthy individuals (p > 0.05).

Conclusions:

  • Serum selenium levels in healthy Korean adults are influenced by gender, with females having higher concentrations.
  • Age does not appear to be a significant determinant of serum selenium levels in this population.
  • These findings contribute to the understanding of selenium homeostasis and provide population-specific reference values.