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A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
09:57

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit

Published on: July 13, 2019

A prospective 7-year survey on central venous catheter-related complications at a single pediatric hospital

M Pinon1, S Bezzio, P A Tovo

  • 1Department of Pediatrics, University of Turin, Turin, Italy.

European Journal of Pediatrics
|March 21, 2009
PubMed

Insights

This study found central venous catheter (CVC) complications in children with serious illnesses occurred less often than expected. Key risk factors included specific diagnoses and younger age, highlighting areas for improved CVC care.

Area of Science:

  • Pediatric Oncology
  • Hematology
  • Immunology
  • Vascular Access Devices

Background:

  • Central venous catheters (CVCs) are essential for managing children with oncological, hematological, and immunological diseases.
  • Understanding the incidence and risk factors of CVC-related complications is crucial for patient safety and optimizing treatment.
  • Previous data on CVC complications in this pediatric population is limited.

Purpose of the Study:

  • To determine the incidence of major CVC-related complications in a large cohort of children with oncological, hematological, or immunological diseases.
  • To identify significant risk factors associated with these CVC complications.
  • To provide valuable data for improving CVC management strategies in pediatric patients.

Main Methods:

  • A 7-year prospective observational study was conducted at a single center.
  • Nine hundred fifteen CVCs were inserted in 748 children, with data collected over 307,846 CVC-days.
  • Complications, including mechanical issues, infections, and thrombosis, were systematically documented and analyzed.

Main Results:

  • The overall complication rate was 0.97 per 1,000 CVC-days, lower than previously reported.
  • Mechanical complications occurred at 0.34/1,000 CVC-days (dislocations 0.30, ruptures 0.04).
  • Infections occurred at 0.56/1,000 CVC-days (bloodstream infections 0.46, tunnel infections 0.10), and thrombosis at 0.06/1,000 CVC-days.
  • Significant risk factors identified included acute lymphoblastic leukemia (ALL) and age ≤3 years for dislocations and tunnel infections; nonmalignant disease for ruptures; ALL for thrombosis; and double-lumen/partially implanted CVCs for bloodstream infections.

Conclusions:

  • The incidence of CVC-related complications in this pediatric cohort is lower than typically reported in the literature.
  • Specific patient diagnoses (e.g., ALL) and younger age (
  • These findings underscore the importance of tailored CVC management protocols based on patient-specific risk factors in pediatric oncology, hematology, and immunology.

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