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Published on: April 27, 2014
Bladder outlet obstruction in painful bladder syndrome/interstitial cystitis
Anne P Cameron1, Jerzy B Gajewski
1Department of Urology, University of Michigan, Ann Arbor, Michigan, USA. annepell@med.umich.edu
Neurourology and Urodynamics
|March 21, 2009
Summary
Nearly half of patients with painful bladder syndrome/interstitial cystitis (PBS/IC) experience bladder outlet obstruction (BOO). Increased PBS/IC severity correlates with higher voiding pressures in these patients.
Area of Science:
- Urology
- Nephrology
- Gynecology
Background:
- Painful bladder syndrome/interstitial cystitis (PBS/IC) commonly presents with obstructive voiding symptoms.
- Dysfunctional voiding may contribute to bladder outlet obstruction (BOO) in PBS/IC patients.
- The relationship between PBS/IC severity and the presence of BOO requires further investigation.
Purpose of the Study:
- To investigate the prevalence of measurable bladder outlet obstruction (BOO) in patients diagnosed with painful bladder syndrome/interstitial cystitis (PBS/IC).
- To determine if increased severity of PBS/IC correlates with the presence and degree of BOO.
Main Methods:
- Retrospective chart review of female patients diagnosed with PBS/IC.
- Analysis of clinical symptom severity, cystoscopy findings (ulcer vs. non-ulcer), and pressure-flow urodynamics (UDPF).
- Definition of BOO based on specific urodynamic cut-off values for maximum flow rate and detrusor pressure.
Main Results:
- 48% of the 231 reviewed PBS/IC patients met criteria for BOO.
- Patients with BOO exhibited significantly lower maximum flow rates and higher detrusor pressures compared to non-obstructed patients.
- Ulcer PBS/IC was associated with lower maximum flow rates and higher detrusor pressures than non-ulcer PBS/IC.
Conclusions:
- A significant proportion of PBS/IC patients (48%) have associated bladder outlet obstruction (BOO).
- Increasing severity of PBS/IC symptoms is linked to elevated voiding pressures.
- These findings suggest BOO is a relevant complication in PBS/IC management.
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