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Related Experiment Videos

[Fournier disease in surgeon's practice].

S A Aliev, S F Rafiev, F S Rafiev

    Khirurgiia
    |March 24, 2009
    PubMed
    Summary

    This study on Fournier disease, a severe scrotal gangrene, found non-clostridial anaerobic bacteria as the primary cause. Aggressive surgical intervention and wound care improved outcomes for patients with this condition.

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    Vestnik khirurgii imeni I. I. Grekova·2016

    Area of Science:

    • Urology
    • Infectious Diseases
    • Surgical Pathology

    Background:

    • Fournier disease, or fulminating scrotal gangrene, is a rapidly progressive necrotizing infection.
    • It affects patients typically between 34-82 years, with varied disease progression (bounded vs. widespread).
    • Common underlying causes include colorectal and urogenital pathologies, trauma, and diabetes mellitus.

    Purpose of the Study:

    • To present treatment results for 17 patients with fulminating scrotal gangrene (Fournier disease).
    • To identify causative agents and risk factors associated with Fournier disease.
    • To evaluate the efficacy of a comprehensive treatment strategy.

    Main Methods:

    • Retrospective analysis of 17 patients diagnosed with Fournier disease.
    • Assessment of underlying etiologies, including colorectal and urogenital pathologies, trauma, and comorbidities like diabetes mellitus.
    • Identification of causative microorganisms, with a focus on non-clostridial anaerobic bacteria.
    • Implementation of active surgical management, including early and staged necrectomy, local wound care, and intensive medical correction of homeostasis disturbances.

    Main Results:

    • Colorectal pathology (8 patients) and urogenital pathology (7 patients) were the most frequent causes.
    • Non-clostridial anaerobic bacteria were identified as the main infectious agents in 88.2% of cases.
    • The overall lethality rate was 29.4% (5 out of 17 patients died).
    • Widespread forms of the disease were observed in 5 patients, while 12 had bounded forms.

    Conclusions:

    • Aggressive surgical management, including early and staged necrectomy, combined with comprehensive local wound care and intensive medical correction, can improve treatment outcomes for Fournier disease.
    • Prompt identification and management of underlying causes and causative agents are crucial.
    • Despite advancements, Fournier disease remains a condition with significant morbidity and mortality.

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