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Related Concept Videos

Decreased Body Temperature01:29

Decreased Body Temperature

A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by sustained extreme cold exposure, and severe...
Responses to Heat and Cold Stress02:45

Responses to Heat and Cold Stress

Every organism has an optimum temperature range within which healthy growth and physiological functioning can occur. At the ends of this range, there will be a minimum and maximum temperature that interrupt biological processes.

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Related Experiment Video

Updated: Jun 24, 2026

Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans
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Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans

Published on: June 2, 2023

Cold exposure increases adiponectin levels in men.

Pascal Imbeault1, Isabelle Dépault, François Haman

  • 1Behavioural and Metabolic Research Unit (Montfort Hospital), School of Human Kinetics, Faculty of Health Sciences, University of Ottawa, Ontario, Canada K1N 6N5. imbeault@uottawa.ca

Metabolism: Clinical and Experimental
|March 24, 2009
PubMed
Summary
This summary is machine-generated.

Cold exposure increases adiponectin levels in healthy men. This rise during shivering is reduced by glucose intake but unaffected by short-term carbohydrate availability changes.

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Last Updated: Jun 24, 2026

Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans
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Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans

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Whole Body and Regional Quantification of Active Human Brown Adipose Tissue Using 18F-FDG PET/CT
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Whole Body and Regional Quantification of Active Human Brown Adipose Tissue Using 18F-FDG PET/CT

Published on: April 1, 2019

Area of Science:

  • Human physiology
  • Metabolic responses to environmental stimuli

Background:

  • Sympathetic nerve activation occurs in adipose tissue during cold exposure.
  • Adiponectin, a key adipose protein, has unknown acute modulation in humans during cold.
  • Understanding adiponectin's response to cold is crucial for metabolic research.

Purpose of the Study:

  • To investigate the acute effects of cold exposure on circulating adiponectin levels in humans.
  • To determine if acute glucose ingestion modulates cold-induced adiponectin changes.
  • To assess the impact of short-term carbohydrate availability on adiponectin response to cold.

Main Methods:

  • Two randomized crossover studies involving healthy men exposed to cold for 120 minutes.
  • Study 1: Ingestion of low or high glucose beverages during cold exposure.
  • Study 2: Cold exposure following low-carbohydrate/exercise or high-carbohydrate diets; plasma adiponectin measured.

Main Results:

  • Cold exposure significantly increased plasma adiponectin levels (~70%) in both studies.
  • A trend for increased adiponectin was observed during cold with low glucose (Control), but not high glucose.
  • Adiponectin increase during cold was independent of short-term dietary carbohydrate availability.

Conclusions:

  • A 120-minute cold exposure significantly elevates adiponectin in young healthy men.
  • Glucose ingestion inhibits the cold-induced rise in adiponectin.
  • Short-term variations in carbohydrate availability do not alter adiponectin's response to cold exposure.