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Updated: Jun 24, 2026
09:13
Implementation of a Nonlinear Microscope Based on Stimulated Raman Scattering
Published on: July 6, 2019
Improvement and analysis of a micro Raman probe
Yuichi Komachi1, Takashi Katagiri, Hidetoshi Sato
1Machida Endoscope Co., Ltd., 6-13-8, Honkomagome, Bunkyo-ku, Tokyo 113-0021, Japan. komachi@machida-eds.co.jp
Applied Optics
|March 24, 2009
Summary
Researchers enhanced the narrowest micro Raman probe (MRP) for improved sensitivity and signal-to-noise ratio. This advanced Raman spectroscopy tool shows effectiveness for in situ measurements of various samples.
Area of Science:
- Spectroscopy
- Materials Science
- Biomedical Engineering
Background:
- Micro Raman probes (MRPs) are crucial for in situ chemical analysis.
- Previous MRPs achieved narrow diameters but required further optimization for performance.
Purpose of the Study:
- To enhance the performance of a 600 micrometer diameter micro Raman probe.
- To improve collection efficiency, signal-to-noise ratio, and spectral range.
- To evaluate the impact of a lens-tipped versus flat tip design.
Main Methods:
- Fabrication of MRPs with integrated high-quality optical filters and a collecting lens.
- Experimental comparison of lens-tipped and flat-tip MRPs.
- Evaluation of optical purity, sensitivity, and viewing area.
- In situ measurements on standard Raman samples, plastics, and human skin.
Main Results:
- The enhanced MRP demonstrated high collection efficiency and a wider collection wavelength.
- Improved signal-to-noise ratio and optical purity were achieved.
- The lens-tipped probe showed superior detection properties compared to the flat-tip probe.
Conclusions:
- The optimized micro Raman probe offers significant improvements for sensitive, in situ chemical analysis.
- The lens-tipped design enhances the probe's effectiveness for diverse sample measurements.
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