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Updated: Jun 24, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Commentary: whose views count in evidence synthesis? And when do they count?
1Chief Executive Officer, Canadian Health Services Research Foundation, Ottawa, ON.
Abstract:
Four recent pieces in Healthcare Policy reveal some disagreement on when and how to involve decision-makers in the process of evidence synthesis. This commentary proposes varying roles for researchers versus managers or policy makers at each of three different stages of synthesis and at the actual point of decision. It also raises the issue of how poorly current processes accommodate the broader conception of evidence held by most managers and policy makers.
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