Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hypertension IV: Drug Therapy and Lifestyle Modifications01:28

Hypertension IV: Drug Therapy and Lifestyle Modifications

Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
Hypertension I: Introduction01:28

Hypertension I: Introduction

Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
Hypertension V: Nursing Management01:23

Hypertension V: Nursing Management

The nursing management of hypertension involves accurately assessing symptoms, making a comprehensive nursing diagnosis, collaborating with patients to set goals, and implementing targeted interventions to mitigate the condition's impact and improve patient well-being.Comprehensive AssessmentThe initial step in nursing care for hypertension involves a thorough patient assessment. It includes evaluating symptoms such as headaches, dizziness, blurred vision, and previous hypertension episodes.
Treatment for Pulmonary Arterial Hypertension: Receptor Tyrosine Kinase Inhibitors and Calcium Channel Blockers01:26

Treatment for Pulmonary Arterial Hypertension: Receptor Tyrosine Kinase Inhibitors and Calcium Channel Blockers

Receptor tyrosine kinase inhibitors (TKIs) and calcium channel blockers (CCBs) are two critical categories of drugs employed in the treatment of pulmonary artery hypertension (PAH). PAH is a disease that causes high blood pressure in the pulmonary arteries, resulting in chest pain, fatigue, and shortness of breath.
TKIs, such as imatinib (Gleevec), are particularly effective in tackling the growth and mitogenic factors that become upregulated in PAH patients. These factors contribute to the...
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[New hypertension guidelines].

Deutsche medizinische Wochenschrift (1946)·2013
Same author

[Are beta blockers no longer the medicines of choice for the treatment of hypertension?].

MMW Fortschritte der Medizin·2007
Same author

[Treating essential hypertension. Are beta blockers still first choice?].

MMW Fortschritte der Medizin·2007
Same author

ESH-ESC guidelines for the management of hypertension.

Herz·2006
Same author

Arterial distensibility, intima media thickness and pulse wave velocity after renal transplantation and in dialysis normotensive patients.

International angiology : a journal of the International Union of Angiology·2005
Same author

Practice guidelines for primary care physicians: 2003 ESH/ESC hypertension guidelines.

Journal of hypertension·2003

Related Experiment Video

Updated: Jun 24, 2026

The Antihypertensive Effects and Mechanisms of Huotan Jiedu Tongluo Decoction in Rats with H-Type Hypertension
05:57

The Antihypertensive Effects and Mechanisms of Huotan Jiedu Tongluo Decoction in Rats with H-Type Hypertension

Published on: May 17, 2024

[Differential hypertensive therapy according to the guidelines].

K H Rahn1

  • 1Universitätsklinikum Münster, Potstiege 42, Münster, Germany. rahn@uni-muenster.de

Der Internist
|March 24, 2009
PubMed
Summary

Lowering blood pressure through lifestyle changes and medications is key to reducing cardiovascular risk. Most patients need multiple antihypertensive drugs to achieve target blood pressure goals.

Area of Science:

  • Cardiology
  • Pharmacology

Context:

  • Hypertension management requires a multifaceted approach combining lifestyle modifications and pharmacotherapy.
  • Achieving target blood pressure is crucial for mitigating cardiovascular risk in hypertensive individuals.

Purpose:

  • To outline the principles of antihypertensive therapy, including target blood pressure goals and available drug classes.
  • To emphasize the necessity of drug treatment, often in combination, for effective blood pressure control.

Summary:

  • Antihypertensive therapy aims to reduce blood pressure and cardiovascular risk using lifestyle changes and medications.
  • Target blood pressure is <140/90 mmHg for all hypertensive patients, and <130/80 mmHg for high-risk groups (e.g., diabetes, chronic kidney disease).
  • First-choice drug classes include diuretics, beta-blockers, calcium antagonists, ACE-inhibitors, and ARBs, with selection based on side effects and comorbidities. Most patients require combination therapy.

Related Experiment Videos

Last Updated: Jun 24, 2026

The Antihypertensive Effects and Mechanisms of Huotan Jiedu Tongluo Decoction in Rats with H-Type Hypertension
05:57

The Antihypertensive Effects and Mechanisms of Huotan Jiedu Tongluo Decoction in Rats with H-Type Hypertension

Published on: May 17, 2024

Impact:

  • Effective blood pressure control significantly lowers cardiovascular risk.
  • Understanding drug selection criteria and the need for combination therapy optimizes patient outcomes.
  • This guidance supports clinicians in managing hypertension and preventing associated complications.