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Updated: Jun 24, 2026

Development and Standardization of an Ex Vivo Micromethod for Intracellular Quantification of Vincristine in Primary ALL Cells by LC-MS/MS
Published on: January 23, 2026
Erroneous administration of vinblastine.
Maciej Barzdo1, Leszek Zydek, Anna Smedra-Kaźmirska
1Department of Forensic Court and Insurance Certification, Medical University of Lodz, ul. Sedziowska 18a, 91-304, Lodz, Poland.
A prescribing error led to an 83-year-old patient receiving a fatal dose of chemotherapy instead of prescribed medication. This case highlights critical medication safety issues in healthcare settings.
Area of Science:
- Pharmacology
- Medical Errors
- Patient Safety
Background:
- An 83-year-old patient presented with unspecified complaints.
- The physician intended to prescribe Vasolastine, a medication for angiopathy.
Observation:
- The physician misspelled Vasolastine as 'Vinplastyna', a non-existent drug.
- A pharmacist dispensed Vinblastine, a chemotherapy agent, instead of the intended medication.
- Community nurses administered Vinblastine daily for seven days.
Findings:
- The patient developed myelophthisis (bone marrow failure) after the seventh dose.
- The patient was admitted to the Intensive Care Ward and subsequently died.
Implications:
- This case underscores the severe consequences of medication errors, including incorrect drug dispensing and administration.
- It highlights the need for robust systems to prevent prescription errors and ensure correct medication dispensing.
- Improved patient safety protocols are crucial to avoid such preventable deaths in clinical practice.
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