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The complete amino acid sequence of bovine antithrombin (ATIII)
H Mejdoub1, M Le Ret, Y Boulanger
1Laboratoire de Biochimie, Centre National de la Recherche Scientifique, Strasbourg, France.
Journal of Protein Chemistry
|April 1, 1991
Abstract:
Bovine antithrombin (ATIII) is a glycoprotein of Mr 56,600. Its primary structure was established using peptide sequences from five different digests. Bovine ATIII exhibits four glcosylation sites as well as human ATIII. The primary structures of bovine and human ATIII were compared: all the residues required for the integrity of the heparin-binding domain are strictly conserved. However, there are differences in the secondary structures of both proteins, bovine and human ATIII.