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Updated: Jun 24, 2026

Studying the Hypothalamic Insulin Signal to Peripheral Glucose Intolerance with a Continuous Drug Infusion System into the Mouse Brain
Published on: January 4, 2018
Psychological aspects in continuous subcutaneous insulin infusion: a retrospective study
Ingo Aberle1, Urte Scholz, Birgit Bach-Kliegel
1Technische Universität Dresden, Department of Psychology, Germany.
Abstract:
The authors aimed to analyze the relation of psychological predictors with medical and psychological therapy success indicators in continuous subcutaneous insulin infusion (CSII). Besides blood glucose control as a medical indicator of therapy success (by means of HbA(1c) levels), the authors assessed treatment satisfaction, depressive symptoms, and quality of life among 51 adult patients on CSII. The authors examined the following psychological factors that were assumed to be associated with outcome variables: coping style, locus of control, and self-efficacy. Self-efficacy correlated positively with all psychological outcome variables. A high external locus of control was related to negative glycaemic outcome and more depressive symptoms. Multiple linear regression analyses revealed that when considering all psychological factors simultaneously, locus of control was the strongest predictor of HbA(1c). For the psychological outcomes, self-efficacy was the most powerful predictor. The authors demonstrated that medical and psychological diabetes-related outcomes were strongly related to psychological factors in adult CSII patients. Patients who felt responsible for the process of CSII therapy showed more positive outcomes; therefore, psychological care can be seen as an important part of diabetes education in CSII therapy.
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