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Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots
Published on: May 21, 2013
Meniscal allograft transplantation
Jonathan D Packer1, Scott A Rodeo
1Laboratory for Soft Tissue Research, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA.
Abstract:
Meniscal allograft transplantation has emerged as a treatment option for selected meniscus-deficient patients to restore normal meniscal function and forestall progressive joint degeneration. Contraindications include diffuse subchondral bone exposure, axial malalignment, and instability. However, a knee may be rendered suitable for meniscus transplantation if combined with chondral resurfacing, osteotomy, and/or ligament reconstruction. Although numerous studies have reported improved clinical outcomes with meniscal allograft transplantation, high-quality studies with control groups are lacking in the literature. This article describes the current indications, graft types and sizing, surgical techniques, and a review of the literature with a focus on the role of concomitant procedures.

