Extrahepatic cholangiocarcinoma: current surgical strategy
Cherif Boutros1, Ponnandai Somasundar, N Joseph Espat
1Department of Hepatobiliary and Surgical Oncology, Roger Williams Medical Center, Boston University School of Medicine, 825 Chalkstone Avenue, Prior 4, Providence, RI 02908, USA.
Surgical Oncology Clinics of North America
|March 25, 2009
Summary
Cholangiocarcinoma, a rare cancer, is the second most common hepatobiliary cancer with rising global incidence. Prognosis for extrahepatic cholangiocarcinoma depends on its location within the biliary tree.
Area of Science:
- Oncology
- Gastroenterology
- Hepatobiliary Medicine
Background:
- Cholangiocarcinoma is a rare malignancy, yet it is the second most frequent hepatobiliary cancer.
- The global incidence of cholangiocarcinoma is increasing.
- Extrahepatic cholangiocarcinoma presents a variable prognosis based on tumor location within the biliary tree.
Purpose of the Study:
- To summarize the current understanding of cholangiocarcinoma, focusing on incidence and prognosis.
- To highlight the significance of tumor location in extrahepatic cholangiocarcinoma outcomes.
Main Methods:
- Review of epidemiological data on cholangiocarcinoma incidence.
- Analysis of prognostic factors in extrahepatic cholangiocarcinoma, particularly location.
Main Results:
- Cholangiocarcinoma incidence is rising globally.
- Prognosis for extrahepatic cholangiocarcinoma is significantly influenced by the specific location along the biliary tree.
Conclusions:
- Cholangiocarcinoma represents a growing global health concern.
- Understanding the anatomical location of extrahepatic cholangiocarcinoma is crucial for predicting patient outcomes.

