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Updated: Jun 24, 2026

Protocols for Testing the Toxicity of Novel Insecticidal Chemistries to Mosquitoes
Published on: February 13, 2019
Human exposure to insecticide products containing pyrethrins and piperonyl butoxide (2001-2003)
Thomas G Osimitz1, Nancy Sommers, Richard Kingston
1Science Strategies, LLC, 600 E Water Street, Suite G, Charlottesville, VA 22902, USA. tom@sciencestrategies.com
Abstract:
Pyrethrum, used as an insecticide for centuries, is derived from dried and ground flowers of Chrysanthemum cinerariaefolium. Its current major use is in insecticide products to the control insects in the home and food handling establishments. We investigated human incidents reported through the American Association of Poison Control Centers (AAPCC) Toxic Exposure Surveillance System (TESS) associated with regulated insecticides containing pyrethrins and piperonyl butoxide (PY/PBO) from 2001 to 2003. Special attention was paid to dermal and respiratory effects. Although there are limitations associated with TESS data, we observed that In view of their widespread use, the data indicates that PY/PBO products can be used with a relatively low risk of adverse effects. Moreover, the data suggest that they are not likely to cause reactions in people with asthma or allergies.
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