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Transient leukoerythroblastosis in a very low birth weight infant with parvovirus B19 infection

Ridvan Duran1, Ulfet Vatansever, Betül Acunaş

  • 1Department of Pediatrics, Trakya University Faculty of Medicine, 22030 Edirne, Turkey. ridvan_duran@yahoo.com

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases
|March 25, 2009
PubMed

Insights

Transient leukoerythroblastosis, a high white blood cell count, can occur in preterm infants. Parvovirus B19 infection is a potential cause to consider in neonates.

Area of Science:

  • Neonatal Medicine
  • Pediatric Hematology
  • Infectious Diseases

Background:

  • Leukoerythroblastosis involves high white blood cell counts with immature myeloid and erythroid cells.
  • Common causes in children include viral infections, juvenile myelomonocytic leukemia, and osteopetrosis.
  • Parvovirus B19 association is rare, previously noted only in one preterm infant.

Observation:

  • A case study of a very low birth weight preterm infant presented with transient leukoerythroblastosis.
  • The condition was associated with parvovirus B19 infection.

Findings:

  • Parvovirus B19 infection can manifest as leukoerythroblastosis in preterm neonates.
  • This association highlights a less common presentation of parvovirus B19.

Implications:

  • High leukocyte counts in neonates warrant consideration of leukoerythroblastosis.
  • Parvovirus B19 infection should be investigated as a potential etiological factor in such cases.
  • Early diagnosis and management are crucial for affected infants.
Abstract

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