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Updated: Jun 24, 2026

A New Method for Inducing a Depression-Like Behavior in Rats

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

Cancer and depression: a prospective study.

L Slovacek¹, B Slovackova, I Slanska

¹University of Defence, Department of Field Internal Medicine, Hradec Kralove, Czech Republic. ladislav.slovacek@seznam.cz

|March 25, 2009

Summary

This summary is machine-generated.

This study screened depression in palliative care female patients, finding a high incidence of 71.8%. Mild depression was prevalent, with a clear association between advanced cancer and depressive symptoms.

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Last Updated: Jun 24, 2026

A New Method for Inducing a Depression-Like Behavior in Rats

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

Area of Science:

Oncology
Psychiatry
Palliative Care

Background:

Psychological distress is common in cancer patients due to symptoms, stigma, and treatment.
Depression affects approximately 25% of palliative care patients and is challenging to identify in advanced illness.
Screening for depression is crucial in palliative care settings.

Purpose of the Study:

To screen for depression among female patients receiving palliative care.
To determine the incidence and severity of depression in this population.
To explore associations between depression and specific cancer types.

Main Methods:

A prospective, cross-sectional study conducted at Charles University Hospital, Czech Republic (2007-2008).
Involved 64 female palliative care patients with a mean age of 60.5 years.
Utilized the Czech version of the Zung Self-Rating Depression Scale (SDS).

Main Results:

The mean SDS score was 56, indicating mild depression in the palliative care group, compared to 38.9 in healthy females.
A high incidence of depression was observed: 71.8% (46 out of 64 patients).
Depression severity varied: 8 severely, 21 moderately, and 17 mildly depressed patients.

Conclusions:

There is a significant association between oncological disease in palliative care and depression.
Specific cancers like lung, endometrium, gallbladder, and melanomas were linked to moderate depression.
Ovarian, breast, brain, ventricle, pancreas head, and buccal cavity cancers were associated with mild depression.