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[Efficacy and safety of 308 nm excimer laser for vitiligo]
Hong-Wei Wang1, Ya-Gang Zuo, Hong-Zhong Jin
1Department of Dermatology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China. whwtyw@263.net
Objective:
To assess the efficacy and safety of the 308 nm excimer laser for the treatment of vitiligo.
Methods:
We treated 170 patients with stable vitiligo by using the 308 nm excimer laser. The lesions of vitiligo were treated one to two times per week for 10-30 times. Efficacies were evaluated every 7 days and 3 days after the treatments were completed. Patients were followed up for two months.
Results:
The rates of "remarkably improved" and "cured" were 67.97% and 32.03% in faces, 54.55% and 27.27% in necks, 63.26% and 26.53% in trunks, 38.84% and 15.70% in limbs, and 0 and 0 in hands and feet. The areas of faces had a better response than those of necks, trunks, or limbs (P < 0.01), and the areas of trunks or limbs had better response than that of hands and feet (P < 0.01).
Conclusion:
The 308 nm excimer laser is safe and effective in treating stable vitiligo and the efficacy varies in different lesion sites.
