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[Clinical characteristics of patients with juvenile localized scleroderma]
1Department of Dermatology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
Objective:
To investigate the clinical characteristics of juvenile localized scleroderma (JLS).
Methods:
The clinical data of 100 outpatients with JLS who were admitted to PUMC Hospital from 2000 to 2008 were retrospectively analyzed.
Results:
Of a total of 100 cases, 51 (51%) were confirmed as linear scleroderma, 26 (26%) as plaque morphea, 26 (26%) as deep morphea, 12 (12%) as generalized morphea, and 15 (15%) as a mixed subtype. Nine patients (9%) had family histories of rheumatic or autoimmune diseases, while 16 (16%) might be triggered by unknown factors. Totally 84 patients underwent antinuclear antibody tests and 38 patients (45.2%) had positive results.
Conclusions:
Linear scleroderma are the most frequent subtype of JLS. Localized scleroderma may be associated with some autoimmune-related causes.
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