Related Experiment Video
Updated: Jun 24, 2026
05:05
Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid
Published on: June 17, 2025
[Treatment of pemphigus with rituximab]
Jun Li1, He-Yi Zheng, Yue-Hua Liu
1Department of Dermatology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China. lijun35@hotmail.com
Abstract:
Pemphigus is a life-threatening autoimmune blistering disease affecting the skin and mucosa. Patients with severe pemphigus require long-term treatment with corticosteroids and other immunosuppressive drugs, which can lead to serious adverse events. Rituximab, a monoclonal antibody directed against the CD20 antigen of B lymphocytes, has been demonstrated to be effective in recalcitrant and life-threatening pemphigus.