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[Research on relationship between coronary lesion and blood stasis syndrome based on coronary angiography]

Jie Wang1, Qing-yong He, Chang-sheng Ma

  • 1Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing.

Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine
|March 26, 2009
PubMed

Insights

Blood stasis (BS) syndrome is linked to more severe coronary lesions in coronary heart disease (CHD) patients. The yang-deficiency subtype of BS syndrome showed a strong correlation with severe coronary constriction.

Area of Science:

  • Cardiology
  • Traditional Chinese Medicine
  • Medical Diagnostics

Background:

  • Coronary heart disease (CHD) poses a significant global health burden.
  • Blood stasis (BS) syndrome is a concept in traditional Chinese medicine often associated with cardiovascular conditions.
  • Understanding the relationship between BS syndrome and coronary atherosclerosis is crucial for comprehensive patient management.

Purpose of the Study:

  • To investigate the association between blood stasis (BS) syndrome and the characteristics of coronary artery lesions in patients diagnosed with coronary heart disease (CHD).
  • To analyze the correlation between specific BS syndrome subtypes and the severity and extent of coronary lesions.

Main Methods:

  • A cohort of 500 patients with confirmed CHD via coronary angiography were enrolled.
  • Patients were classified based on traditional Chinese medicine syndrome differentiation, specifically identifying BS syndrome and its subtypes.
  • Statistical analysis was performed to compare coronary lesion parameters (number of affected branches, degree of constriction) between BS syndrome and non-BS syndrome groups, as well as among different BS subtypes.

Main Results:

  • Patients with BS syndrome exhibited a significantly higher number of affected coronary branches (2.28 vs. 2.07) and more severe coronary lesions compared to non-BS syndrome patients.
  • The yang-deficiency subtype of BS syndrome was associated with the highest number of affected branches (2.58) and a higher prevalence of severe or moderate coronary constriction.
  • A significant correlation was observed between the yang-deficiency BS subtype and severe coronary constriction (correlation distance 0.1899).

Conclusions:

  • A significant relationship exists between blood stasis (BS) syndrome and the extent and severity of coronary lesions in patients with coronary heart disease (CHD).
  • The yang-deficiency subtype of BS syndrome is particularly associated with more extensive and severe coronary artery disease.
  • These findings support the integration of BS syndrome assessment in the evaluation and management of CHD.
Abstract

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