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Updated: Jun 24, 2026

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

Trends in multidrug-resistant tuberculosis in Scotland, 2000-7.

L F Anderson¹, I F Laurenson, O Blatchford

¹Department of Public Health Sciences, University of Edinburgh, Edinburgh, UK. laura_f_anderson@hotmail.com

Euro Surveillance : Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin

|March 26, 2009

Summary

Multidrug-resistant tuberculosis (MDR TB) cases in Scotland are primarily linked to international transmission, highlighting the need for global control efforts. Improved directly observed treatment (DOT) and extended follow-up are crucial for managing MDR TB in Scotland.

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The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray

Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray

Published on: April 25, 2014

Area of Science:

Public Health
Infectious Diseases
Epidemiology

Background:

Multidrug-resistant tuberculosis (MDR TB) incidence rose in the UK and Scotland in 2007.
Previous studies identified MDR TB risk factors in the UK, but not specifically in Scotland.

Purpose of the Study:

To examine demographic, clinical characteristics, and treatment outcomes of MDR TB cases in Scotland (2000-2007).
To identify risk factors and inform control strategies for MDR TB in Scotland.

Main Methods:

Utilized Enhanced Surveillance of Mycobacterial Infections (ESMI) data.
Analyzed 11 culture-positive MDR TB cases notified in Scotland between 2000 and 2007.

Main Results:

Five MDR TB cases were notified in 2007.
Most patients were young (15-44 years), female, unemployed, and born outside the UK, with recent travel/arrival from high-incidence regions.
Unlike UK findings, a history of previous TB diagnosis was not a significant risk factor in this Scottish cohort.

Conclusions:

Findings suggest primary resistance due to MDR TB transmission in high-incidence countries, emphasizing international control efforts.
Recommendations include increasing directly observed treatment (DOT) and extending follow-up for MDR TB patients in Scotland.
Identifying high-risk groups is essential for effective community-based disease control.