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Metastatic renal cell cancer: interleukin-2 toxicity induced by contrast agent injection
A S Abi-Aad1, R A Figlin, A Belldegrun
1Department of Surgery, UCLA School of Medicine.
Abstract:
We describe a clinical syndrome occurring after contrast medium injection in patients who previously received recombinant interleukin-2 (rIL-2) and recombinant interferon-alpha 2A treatment for metastatic renal cancer. The clinical picture mimics many aspects of rIL-2-related systemic side effects. The patients were managed conservatively but the potential for severe manifestations can occur, requiring more intensive treatment.