Related Experiment Video
Updated: Jun 24, 2026

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
Published on: January 28, 2020
Short and long-term labour market consequences of coronary heart disease: a register-based follow-up study
Marie Kruse1, Jan Sørensen, Michael Davidsen
1National Institute of Public Health, Copenhagen, Denmark. mak@niph.dk
Insights
Individuals with coronary heart disease (CHD) are at higher risk of leaving the labor market early. Cardiac rehabilitation should focus on helping younger patients and manual laborers return to work.
Area of Science:
- Cardiology
- Public Health
- Occupational Medicine
Background:
- Coronary heart disease (CHD) significantly impacts individuals' lives, including their ability to maintain labor market participation.
- Early withdrawal from employment can have substantial socioeconomic consequences for individuals with CHD and society.
Purpose of the Study:
- To quantify the extent to which individuals with CHD exit the labor market prematurely compared to those without CHD.
- To explore the implications of labor market withdrawal for cardiac rehabilitation strategies.
Main Methods:
- Utilized the Danish National Cohort study to identify individuals with CHD.
- Employed Cox regression analysis to compare long-term withdrawal risks between matched CHD and non-CHD cohorts over a 23-year follow-up period.
Main Results:
- In the year post-admission, 79% of individuals with CHD remained in the workforce versus 93% of controls.
- Individuals with CHD faced a 32% higher risk of labor market withdrawal (Hazard Ratio: 1.32), resulting in 0.8 years less on average.
- Younger individuals (under 60) and manual laborers with CHD showed a particular need for rehabilitation support to maintain employment.
Conclusions:
- Individuals with CHD exhibit a significantly elevated risk of labor market withdrawal.
- Younger patients and manual laborers with CHD appear to encounter greater challenges in sustained employment.
- Enhanced focus on labor market reintegration within cardiac rehabilitation programs may prove beneficial for these specific subgroups.
Objective:
The aim of this study was to analyse to what extent individuals with coronary heart disease (CHD) leave the labour market earlier than individuals without CHD and to discuss the implications for rehabilitation.
Data And Methods:
Individuals with CHD were identified from the Danish National Cohort study and were followed from the year of their first hospital admission for CHD and onwards for up to 23 years. Individuals with CHD were individually matched with individuals without CHD. We analysed their short-term labour market participation and compared the long-term withdrawal risk for the two groups through Cox regression.
Results:
In the year after the first CHD-related admission, 79% of individuals with CHD maintained their labour force participation compared with 93% of individuals without CHD. Individuals with CHD had a hazard ratio of 1.32 for withdrawal compared with their matched counterparts. This means that the individuals with CHD were on the labour market, on average, for 0.8 years less than the individuals without CHD. Stratified analyses showed that, in particular, individuals with CHD aged below 60 years and individuals employed as manual labour may benefit from cardiac rehabilitation, which aims to maintain labour market participation.
Conclusion:
Individuals with CHD have a significantly increased risk of withdrawing from the labour market. Especially younger individuals and those employed as manual labour seem to have greater problems in maintaining labour market participation. This suggests that greater focus in cardiac rehabilitation on returning these individuals to the labour market might be worthwhile.
Related Concept Videos
Longitudinal Studies
Coronary Artery Disease III: Clinical Manifestations
Acute Coronary Syndrome III: Diagnostic Studies
Coronary Artery Disease I: Introduction
Coronary Artery Disease V: Interprofessional Care
Coronary Artery Disease IV: Preventive Measures