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Related Experiment Video

Updated: Jun 24, 2026

Tumor Treating Field Therapy in Combination with Bevacizumab for the Treatment of Recurrent Glioblastoma
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Tumor Treating Field Therapy in Combination with Bevacizumab for the Treatment of Recurrent Glioblastoma

Published on: October 27, 2014

[Bevacizumab and invasive procedures: practical recommendations].

V Gounant1, B Milleron, J Assouad

  • 1Service de Pneumologie et réanimation respiratoire, Hôpital Tenon, AP-HP, Université Paris VI, Paris, France. valerie.gounant@tnn.aphp.fr

Revue Des Maladies Respiratoires
|March 26, 2009
PubMed
Summary
This summary is machine-generated.

Bevacizumab improves survival in non-small cell lung cancer but increases bleeding risks. Recommendations are provided for managing invasive procedures during treatment.

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Published on: April 16, 2019

Area of Science:

  • Oncology
  • Vascular Biology

Context:

  • Bevacizumab, an anti-angiogenic drug, is a first-line chemotherapy for metastatic non-small cell lung cancer.
  • Its mechanism involves inhibiting vascular endothelial growth factor (VEGF), crucial for scar formation and hemostasis.
  • This anti-angiogenic action can lead to increased bleeding risks, particularly with invasive procedures.

Purpose:

  • To analyze the specific risks of bleeding associated with invasive procedures in patients treated with Bevacizumab.
  • To provide practical recommendations for managing these risks in clinical practice.

Summary:

  • Bevacizumab combined with platinum-based chemotherapy improves survival in metastatic non-small cell, non-squamous bronchial carcinoma.
  • The drug's anti-angiogenic properties inhibit scar formation, potentially increasing bleeding complications.
  • Recommendations include specific delays between device implantation, Bevacizumab initiation, and surgical procedures.

Impact:

  • Provides evidence-based guidelines for safe management of patients undergoing invasive procedures while on Bevacizumab therapy.
  • Aims to minimize bleeding complications and optimize patient outcomes in non-small cell lung cancer treatment.
  • Highlights the importance of multidisciplinary team approach for managing patients receiving Bevacizumab.