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Updated: Jun 24, 2026

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
Published on: February 6, 2020
High-load, oligomeric monoamine hydrochloride: Facile generation via ROM polymerization and application as an
Diana S Stoianova1, Lei Yao, Alan Rolfe
1Materia Inc., 60 N. San Gabriel Blvd., Pasadena, CA 91107.
Abstract:
A new high-load, oligomeric monoamine hydrochloride (OMAm*HCl) derived from ring-opening metathesis polymerization (ROMP) of norbornene methylamine is reported. This oligomeric amine has been shown to be an effective scavenger of acid chlorides, sulfonyl chlorides and isocyanates. The reagent can be synthesized in a straightforward protocol from the Diels-Alder reaction of dicyclopentadiene (DCPD) 1 with allylamine (neat), formation of the corresponding ammonium salt and subsequent ROM polymerization to afford the desired oligomeric ammonium salts.
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