Related Experiment Video
Updated: Jun 24, 2026
In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
Advantages of using a ray-traced, three-dimensional rendering system for spectral domain Cirrus HD-OCT to visualize
Carl Glittenberg1, Ilse Krebs, Christiane Falkner-Radler
1Ludwig Boltzmann Institute for Retinology and Biomicroscopic Laser Surgery, Department of Ophthalmology, Rudolf Foundation Clinic, Vienna, Austria.
Background And Objective:
To create a ray-traced, three-dimensional display system for Cirrus high-definition optical coherence tomography (Carl Zeiss Meditec, Inc., Dublin, CA) that improves the visualization of subtle structures of the vitreoretinal interface.
Patients And Methods:
High-definition optical coherence tomography (HD-OCT) data for epiretinal membranes (17 eyes), macular holes (11 eyes), and posterior vitreal detachments (17 eyes) were collected. A display system that visualizes the acquired data using ray-tracing algorithms was designed and compared with the Cirrus HD-OCT 2.0 advanced visualization software system. The area around the vitreoretinal interface was visualized using a 100-microm-thick internal limiting membrane (ILM) fitted slab as well as ILM and retinal pigment epithelium surface reconstructions.
Results:
Subtle structures could be visualized more distinctly using the ray-traced, three-dimensional rendering software.
Conclusion:
A ray-traced visualization system improves the visualization of subtle structures in and around the vitreoretinal interface.