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649
The effect of sacral nerve stimulation on uterine activity: a pilot study
B Govaert1, J Melenhorst, G Link
1Department of surgery, Medical University Centre Maastricht, Maastricht, The Netherlands.
Summary
Sacral nerve stimulation (SNS) may inhibit uterine activity in premenopausal women. Further research is needed to determine the effects of SNS on conception and pregnancy, as current findings are preliminary.
Area of Science:
- Gynecology
- Neurology
Background:
- Sacral nerve stimulation (SNS) treats fecal incontinence and constipation.
- The impact of SNS on uterocervical function is not well understood.
- Current advice suggests disabling SNS during pregnancy or delaying implantation until after childbearing.
Purpose of the Study:
- To assess the influence of SNS on nonpregnant uterine activity.
- To utilize diagnostic ultrasound for non-invasive uterine wave recordings.
Main Methods:
- Six patients with implanted SNS were enrolled.
- Ultrasound recordings captured uterine activity with SNS off and at three stimulation frequencies.
- Uterine activity was analyzed by wave frequency and direction.
Main Results:
- Premenopausal patients: Endometrial activity observed off; two maintained activity with SNS on, one showed cessation.
- Postmenopausal patients: No endometrial activity observed off; one showed activity at 21 Hz with SNS on.
Conclusions:
- SNS appears to have an inhibitory or no effect on uterine activity in premenopausal women.
- Preliminary results do not support guidelines for SNS use during conception or pregnancy.
- A larger study is required to investigate the significance of SNS effects on uterine activity in premenopausal women.
