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[Post-amoxicilline neutropenic rectitis in an immunocompetent patient: a case report]
M-P Massoure1, P Sockeel, M Richecoeur
1Service de pathologie digestive, hôpital d'instruction des armées Clermont Tonnerre, rue du colonel-Fontferrier, 29240 Brest Naval, France. cnemassoure@hotmail.fr
Abstract:
We report a 38-year-old immunocompetent patient who presented with a neutropenic rectitis after a treatment by amoxicillin for nasopharyngitis. Neutropenic colitis is a digestive wall inflammation, preferentially localized in the ileo-caecal area and the right colon, which leads to necrosis and sepsis, and usually occurs in neutropenic patients treated by chemotherapy with an incidence of 6%. It is a serious and often lethal disease. The treatment is supportive, and surgery is limited to the occurrence of complications (perforation, bleeding). Neutropenic colitis occurring in a rectal location after antibiotic therapy in an immunocompetent patient has been rarely described.
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Etiology
Three primary contributing factors have been identified.