Related Experiment Video
Updated: Jun 24, 2026

Studying the Epithelial Effects of Intestinal Inflammation In Vitro on Established Murine Colonoids
Published on: June 2, 2023
Epidemiology of inflammatory bowel disease among children in Poland. A prospective, population-based, 2-year study,
Katarzyna Karolewska-Bochenek1, Izabella Lazowska-Przeorek, Piotr Albrecht
1Department of Pediatric Gastroenterology and Nutrition, Medical University of Warsaw, Ul. Dzialdowska 1, PL-01-184 Warsaw, Poland. kasiabochenek@hotmail.com
Insights
The incidence of pediatric inflammatory bowel disease (IBD) in Poland is lower than in Western countries, with a higher relative proportion of ulcerative colitis (UC) and indeterminate colitis (IC). Further research may be needed to explore potential underdiagnosis.
Area of Science:
- Pediatric Gastroenterology
- Epidemiology
- Inflammatory Bowel Disease Research
Background:
- Pediatric inflammatory bowel disease (IBD) incidence is increasing globally.
- No prior prospective epidemiological studies on pediatric IBD in Poland existed.
- This study addresses the need for data on pediatric IBD in Poland.
Purpose of the Study:
- To determine the incidence of new pediatric IBD cases in Poland.
- To characterize new pediatric IBD diagnoses between 2002 and 2004.
- To compare Polish pediatric IBD rates with those in Western countries.
Main Methods:
- Data collected from 24 pediatric gastroenterology centers nationwide.
- Diagnosis of IBD confirmed through clinical, radiological, endoscopic, and histological evaluations.
- Analysis of patient records for new IBD diagnoses.
Main Results:
- Overall pediatric IBD incidence was 2.7 cases/100,000 children/year.
- Crohn's disease (CD) incidence: 0.6; ulcerative colitis (UC): 1.3; indeterminate colitis (IC): 0.8.
- Incidence higher in adolescents (3.7/100,000) than younger children (1.8/100,000).
Conclusions:
- Pediatric IBD incidence in Poland is lower than in Western nations.
- UC and IC constitute a larger proportion of IBD cases in Poland compared to Western countries.
- Findings suggest potential underdiagnosis or misdiagnosis of pediatric IBD in Poland.
Background/Aims:
The incidence of pediatric inflammatory bowel disease (IBD) in Western countries is on the rise. No prospective studies have been conducted on the epidemiology of pediatric IBD in Poland. The aim of the study was to define the characteristics of new pediatric IBD and assess the incidence of new IBD among children in Poland between 2002 and 2004.
Methods:
Patient records from 24 pediatric gastroenterology centers servicing the whole population of Poland were collected. IBD diagnosis was based on clinical, radiological, endoscopic and histological features.
Results:
There were 491 new IBD patients, representing an overall incidence of IBD of 2.7 cases/100,000 children/year. The incidence of Crohn's disease (CD) was 0.6, ulcerative colitis (UC) 1.3, and indeterminate colitis (IC) 0.8. The age-related incidence of IBD was 1.8 in the 0- to 10-year-old age group, rising to 3.7 for the 11- to 18-year age group.
Conclusions:
The overall incidence of IBD (as well as CD, UC and IC) in Poland is lower than that in Western countries. The relative contribution of UC and IC to the overall IBD incidence is higher in Poland than in most Western countries. These findings may suggest a tendency towards under- or misdiagnosis.
Related Concept Videos
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease III: Crohn's Disease
Inflammatory Bowel Disease II: Ulcerative Colitis
Inflammatory Bowel Disease I: Introduction
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
