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Updated: Jun 24, 2026

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
Published on: March 31, 2021
Fluoride has a beneficial effect on root caries
1Department of Public Health, NHS Forth Valley, Stirling, Scotland, UK.
Data Sources:
Medline and the Cochrane Oral Health Group trials register were searched for suitable studies.
Study Selection:
Papers were screened independently by two authors. Randomised controlled trials (RCT), controlled trials and uncontrolled longitudinal studies of at least 3 months' duration that investigated activity and/ or incidence of root caries and were published in English were included.
Data Extraction And Synthesis:
Because of wide variation between clinical parameters evaluated for caries activity, a qualitative synthesis was presented.
Results:
Six studies met the inclusion criteria, five of which were RCT.
Conclusions:
The available studies suggest that increasing the regular daily delivery of fluoride has a beneficial effect, reducing root caries.
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