Related Experiment Video
Updated: Jun 24, 2026

13:22
Kinase Inhibitor Screening In Self-assembled Human Protein Microarrays
Published on: October 23, 2019
High-throughput screening of catalytically inactive mutants of protein tyrosine phosphatases (PTPs) in a
Hongyan Sun1, Lay Pheng Tan, Liqian Gao
1Department of Chemistry, National University of Singapore, 3 Science Drive, Singapore 11754.
Abstract:
We report herein a novel phosphopeptide microarray capable of noncovalently "trapping" catalytically inactive mutants of protein tyrosine phosphatases (PTPs), and its application in high-throughput determination of PTP substrate specificity.

